Item type:Thesis, Open Access

Häufigkeit zentraler schlafbezogener Atmungsstörungen mit Differenzierung nach der Cheyne-Stokes-Atmung bei Patienten mit einer Herzinsuffizienz und eingeschränkter systolischer linksventrikulärer Pumpfunktion (Ejektionsfraktion ≤ 50 %)

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2013-08-13

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Philipps-Universität Marburg
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Abstract

The prevalence of sleep-disordered breathing in patients with chronic heart failure seems to be remarkably high. The aim of this study was to investigate the prevalence of sleep-disordered breathing especially of Cheyne-Stokes respiration in chronic heart failure and with impaired systolic left ventricular function (ejection fraction ≤ 50 %). A total of 224 consecutive patients (58 females; 166 males; mean age 59,2 ± 14,3 years) with chronic heart failure and impaired systolic left ventricular function (ejection fraction ≤ 50 %) were screened by cardiorespiratory polysomnography for the presence and type of sleep-disordered breathing. Sleep apnea was classified as obstructive or central according to the majority of events. The sleep-disordered breathing was defined according to the apnea-hypopnea index (AHI) as follows: no sleep-disordered breathing (< 5/h), mild (≥ 5/h), moderate (> 15/h) and severe (≥ 30/h). In our cohort the prevalence of sleep-disordered breathing was 71 % (43 % ZSA, 28 % OSA). Approximately 24 % of the patients have a Cheyne-Stokes respiration, however, there was no significant difference betweeen mild, moderate and severe central sleep apnea. Taken together our results suggest a high prevalence of sleep-disordered breathing in patients with chronic heart failure. Because of their high prognostic implications, risk stratification and identification of patients eligible for special sleep-disordered breathing treatment, screening for such disorders should be part of every heart failure work-up.

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Dates
Created: 2013Issued: 2013-08-13Updated: 2013-08-13
DOI
https://doi.org/10.17192/z2013.0453
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
Cheyne-Stokes respirationschlafbezogene Atemstörungensleep disordered breathingheart failureSchlaf-Apnoe-SyndromCheyne-Stokes-Atmungsleep apnoea
DFG-subjects
Herzinsuffizienz
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2013.0453
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Duman, Ergün (1042405913): Häufigkeit zentraler schlafbezogener Atmungsstörungen mit Differenzierung nach der Cheyne-Stokes-Atmung bei Patienten mit einer Herzinsuffizienz und eingeschränkter systolischer linksventrikulärer Pumpfunktion (Ejektionsfraktion ≤ 50 %). : Philipps-Universität Marburg 2013-08-13. DOI: https://doi.org/10.17192/z2013.0453.

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