Item type:Thesis, Open Access

Die Expression des Progesteron Rezeptors in Korrelation mit dem erbB2 Onkoprotein und dem Jak – STAT Signalweg in Abhängigkeit von Tumorgrad und gynäkologischer Komorbidität in humanen Meningeomen

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Date

2006-11-15

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Philipps-Universität Marburg
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Abstract

Progesterone receptor expression is frequently observed in human menigeomas. The function and the oncologic relevance of progesterone receptor expression is not known. Further it is not clear which signalling pathways are important for progesterone receptor expression. The expression of the progresterone receptor was correlated with the expression of erbB2 oncoprotein, the Jak - STAT signalling pathway and gynecological comormbidity. It was found, that high-grade meningeomas, such as atypical and anaplastic meningeomas, show less progesterone receptor and erbB2 expression than the low grade human meningeomas. Maybe progesterone receptor expression is more a feature of differentiation than tumor progression.

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Dates
Created: 2006Issued: 2006-11-15Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2006.0779
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
erbB2Progesteron RezeptorJak - STAT SignalwegMeningeomeher2neuJak - STATProgesteroneMeningeoma
DFG-subjects
ProgesteronMeningeomOnkogen HER-2/neuOnkogen
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2006.0779
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Rellecke, Solvejg (132263831): Die Expression des Progesteron Rezeptors in Korrelation mit dem erbB2 Onkoprotein und dem Jak – STAT Signalweg in Abhängigkeit von Tumorgrad und gynäkologischer Komorbidität in humanen Meningeomen. : Philipps-Universität Marburg 2006-11-15. DOI: https://doi.org/10.17192/z2006.0779.

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This item has been published with the following license: In Copyright