Auswirkungen einer neuromuskulären Blockade auf den Leckagedruck der ProSeal®-Larynxmaske
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Philipps-Universität Marburg
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Abstract
Background:
The ProSeal®-Laryngeal mask airway (PLMA) is increasingly
used for surgical procedures that might require the
intraoperative use of neuromuscular blocking agents.
The airway seal of the PLMA depends on the interplay of the surrounding
soft tissue of the neck and the cuff of the mask. An intraoperative
neuromuscular blockade could lead to a decrease of the airway
leak pressure (Pleak) secondary to the relaxation of the muscles
of the neck. With this study we tested the hypothesis that a neu−
romuscular blockade can result in a decreased Pleak of the PLMA.
Methods:
The Pleak of the PLMAwas studied in 73 female patients
under total intravenous anaesthesia with propofol (0,1-0,15
mg/kg/min) and remifentanil (0,1-0,3 mg/kg/min) before
and after a complete neuromuscular blockade produced by intra−
venous injection of 0.6 mg/kg Rocuronium. Results: The Pleak
decreased by more than 10% of the baseline Pleak in 8 out of 73
patients (11%); however, in the entire study population there
was no significant difference between the mean baseline Pleak
(28,5 +/- 7,3 cm H2O) and the mean Pleak after complete neuromus−
cular blockade (29,1 +/- 7,0 cm H2O); (p = 0,128).
Conclusion:
No general correlation between application of a neuromuscular
blocking agent and a decrease of the mean Pleak was found. How−
ever, the decrease of the Pleak by more than 10% in 11% of the pa−
tients shows that in certain patients the application of neuro−
muscular blocking agents can result in a decreased Pleak of the
PLMA and indicates the necessity to control the Pleak of the
PLMA under complete muscle paralysis preoperatively when
neuromuscular blocking agents are used.
Review
Metadata
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Supervisor:
Dates
Created: 2007Issued: 2007-09-20Updated: 2011-08-10
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
LeckagedruckProSeal®-LarynxmaskeNeuromuscular BlockadeProSeal®-Laryngeal Mask AirwayNeuromuskuläre BlockadeAirway Leak Pressure
DFG-subjects
Maschinelle BeatmungAtemwegNarkose
DDC-Numbers
610
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Hoch, Nina: Auswirkungen einer neuromuskulären Blockade auf den Leckagedruck der ProSeal®-Larynxmaske. : Philipps-Universität Marburg 2007-09-20. DOI: https://doi.org/10.17192/z2007.0446.
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This item has been published with the following license: In Copyright