Synthese von neuartigen, Disulfid-verknüpften, bioabbaubaren Polyethylenglykol-Polyethylenimin-Copolymeren zur Anwendung in der Gentherapie
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Philipps-Universität Marburg
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The aim of this dissertation is to synthesize the novel biodegradable, with disulfide bridges linked PEG-PEI copolymers, which are utilized as non-viral vectors in gene therapy. The DNA-polyplexes of the copolymers were characterized and investigated in respect to their suitability as gene vectors for the application in vivo.
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This item has been published with the following license: In Copyright