7-Tesla-Ultrahochfeld Magnetresonanztomographie im Kopfund Halsbereich mittels 64-Kanal-Signaldetektion und integrierter paralleler 16-Kanal-Sendespule
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Philipps-Universität Marburg
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Abstract
Magnetic Resonance Imaging (MRI) has proven to be a valuable diagnostic tool in
everyday clinical practice and has constantly evolved since its introduction. For example,
the first MRI was recently cleared for clinical use by the United States Food and Drug
Administration. With a higher magnetic field strength, the physical effects and parameters
change, which can have a positive (contrast enhancing effect) but also a negative (artifact
enhancing) effect on the imaging process. For example, for technical reasons, it is not
currently possible to generate a whole-body image at a field strength of 7T, as is possible
at 1,5T, for example. Current imaging at 7T MRIs is mainly limited to local areas such
as the brain, foot, arm, or knee joint. Based on the great demand from the clinical field to
extend the Bildfeld /engl.: Field of View (FOV), the research question of this dissertation
arises:
With the current state of the art, considering the maximum available transmit and
receive channels offered by a current commercial 7T-MRI, is it possible to generate a
FOV covering the head and neck region?
This problem was solved by the development of morphologically adapted signal generators
as well as signal detectors. The FOV was extended from the brain region to the neck
region at 7T. The developed hardware was designed, simulated, constructed, tested, and
compared with a commercially available 7T Brain Coil. An advance on the current state
of the art was quantified.
The newly developed methods for designing and constructing the transmit and receive
structure at 7T, as well as the hardware used to test its functionality, have been directly
used and published in modified form in similar MRI research projects at a field strength
of 3T.
In summary, this project has laid the foundation for both clinical imaging and further
research in the combined head and neck region for 7T-MRI. The impact of this project
is expected to be seen in clinical trials over the next few years. Limiting factors such as
SAR can be optimized by software measures and the control of the coils in further PhD
work to optimize the imaging process.
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Dates
Created: 2022Issued: 2023-05-02Updated: 2023-05-02
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
7 TeslaMRTNeurocoil-array;CoilMRT Spule;UHF
DFG-subjects
Kopf-HalsspuleUHF-MRT;
DDC-Numbers
610
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May, Markus W.: 7-Tesla-Ultrahochfeld Magnetresonanztomographie im Kopfund Halsbereich mittels 64-Kanal-Signaldetektion und integrierter paralleler 16-Kanal-Sendespule. : Philipps-Universität Marburg 2023-05-02. DOI: https://doi.org/10.17192/z2022.0329.