Item type:Thesis, Open Access

Crosslinking studies of the bacterial RNase P holoenzyme and functional characterisation of the novel protein-only RNase P from Arabidopsis thaliana

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Date

2012-09-14

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Publisher

Philipps-Universität Marburg
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Abstract

Ribonuclease P (RNase P) is the ubiquitous processing enzyme that generates the mature 5'-termini of tRNA molecules. In Bacteria and Archaea the enzyme is a ribonucleoprotein, whereas in some Eukarya the RNAse P is exclusively proteinaceous. This work is focused on two topics: (i) crosslinking studies of bacterial RNase P holoenzyme utilizing novel 2’- ribooligonucleotides and (ii) functional investigations to the catalytical mechanism of recently discovered protein-only RNase P from Arabidopsis thaliana.

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Dates
Created: 2012Issued: 2012-09-14Updated: 2012-09-28
DOI
https://doi.org/10.17192/z2012.0778
Faculty
Fachbereich Pharmazie
Publisher
Philipps-Universität Marburg
Language
eng
Data types
DoctoralThesis
Keywords
Proteinaceous RNase PCrosslinkingKineticsCatalytical mechanism
DFG-subjects
Endoribonuklease P
DDC-Numbers
500
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2012.0778
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Pavlova, Liudmila Viktorovna: Crosslinking studies of the bacterial RNase P holoenzyme and functional characterisation of the novel protein-only RNase P from Arabidopsis thaliana. : Philipps-Universität Marburg 2012-09-14. DOI: https://doi.org/10.17192/z2012.0778.

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