Item type:Thesis, Open Access

Untersuchung der Hemisphärendominanz während mentaler Rotation mittels funktioneller Magnetresonanztomographie und funktioneller transkranieller Dopplersonographie

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Date

2010-08-02

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Philipps-Universität Marburg
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Abstract

The aim of the present study was to investigate specific activation patterns and potential gender differences during mental rotation and to investigate whether fMRI and fTCD lateralize hemispheric dominance concordantly. Regional brain activation and hemispheric dominance during mental rotation (cube perspective test) were investigated in ten female and ten male healthy subjects using fMRI and fTCD. Our findings indicate that the neural basis of mental rotation depends on a widespread bilateral network: Significant activation was found in the superior parietal lobe, at the parieto-occipital border, in the middle and superior frontal gyrus bilaterally and the right inferior frontal gyrus. Men tended to show more activation in the right hemisphere using fTCD and more activation in frontal and parieto-occiptal regions of the right hemisphere using fMRI. Hemispheric dominance for mental rotation determined by fMRI and fTCD correlated well, but did not show concordant results in every single subject. Hemispheric lateralization of complex cortical functions such as spatial rotation therefore should be investigated using multimodal imaging approaches, especially if used clinically as a tool for the presurgical evaluation of patients undergoing neurosurgery.

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Dates
Created: 2010Issued: 2010-08-02Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2010.0394
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
mental rotationfunktionelle transkranielle Dopplersonographiefuncional magnetic resonance imagingfunktionelle MagnetresonanztomographieMentale Rotationfunctional transcranial Doppler sonography
DFG-subjects
Mentale Rotationfunktionelle transkranielle Dopplersonographiefunktionelle Magnetresonanztomographie
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2010.0394
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Plate, Annika (141920270): Untersuchung der Hemisphärendominanz während mentaler Rotation mittels funktioneller Magnetresonanztomographie und funktioneller transkranieller Dopplersonographie. : Philipps-Universität Marburg 2010-08-02. DOI: https://doi.org/10.17192/z2010.0394.

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