Charakterisierung und Training frontaler Dysfunktionen bei juveniler myoklonischer Epilepsie (JME)
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Philipps-Universität Marburg
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Abstract
The main goal of the study was the creation of an intervention program specifically aimed at
people with juvenile myoclonic epilepsy trying to improve their aware- and mindfulness in order to
better cope with daily psychosocial struggles caused by this disease.
To measure the effectiveness psychometric and neuropsychological tests were used at the start
of, end of, and six months after the intervention. On the one hand alexithyma, mood and social
skills were key aspects to the psychometric tests. On the other hand cognition, attention,
memory, and executive functions were tested in the neuropsychological assessments.
This intervention program is based on a metacognitive training program for schizophrenia which
also includes theory of mind (ToM) elements. Therefore the training was specifically modified for
JME.
That meant each person in the sample participated in a five week training program which initially
taught the psychoeducational basis of JME, followed by relaxation and ToM exercises based on
MCT.
Additionally, the participants were given homework for each week manifesting the learned
methods. All that combined enhanced the social cognition and overall coping with JME.
Not all tests were significant, but some results definitely indicated the effectiveness of this
intervention. For example, the significance in self-efficacy increased immediately after the training
and also in the six months later follow up session. The results of the epilepsy management
questionnaire showed a better understanding and coping with JME. Scores for overall alexithymia
and difficulties in emotion identification increased from post training to the six month follow up
session. Furthermore, significant effects of alexithyma, like the perception of feelings, indicated an
improvement in awareness and social cognition. Some tests weren’t significant but trends in
reflexibility, externally oriented thinking or neuropsychological tests like attention and working
memory confirmed the efficiency of the training in different kinds of ways. Other than the results
just mentioned, the patient’s stress levels decreased significantly after each module. Due to long
term seizure-free periods, experienced by all participants, a further reduction in this matter could
not be properly measured. With the only exception being one patient who had a single seizure
within the 12 months prior the intervention.
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Presently there’re only few therapy options for patients with JME. The method discussed in this
paper still needs further validation and elaboration to confirm it’s results. However, the most
effective therapy for JME patients would most likely be a combination of this specific MCT and
pharmacological treatments.
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Dates
Created: 2023Issued: 2024-04-18Updated: 2024-04-18
Faculty
Medizin
Language
ger
Data types
DoctoralThesis
DDC-Numbers
610
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Huber, Anna-Sophia: Charakterisierung und Training frontaler Dysfunktionen bei juveniler myoklonischer Epilepsie (JME). : Philipps-Universität Marburg 2024-04-18. DOI: https://doi.org/10.17192/z2023.0566.