Item type:Thesis, Open Access

Bewertung quantitativer sonografischer Gewebetypisierung und Längenbestimmung der Cervix uteri als neuer Prädiktor für Cervixinsuffizienz und Frühgeburtlichkeit

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Date

2007-06-08

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Philipps-Universität Marburg
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Abstract

OBJECTIVE: This study was to evaluate the predictice value of the uterine cervix tissue with the use of quantitative ultrasound grey level analysis and cervical length for preterm delivery. STUDY DESIGN: Sixty-eight patients with preterm labor between 20 and 35 weeks of gestation were included. When two-dimensional transvaginal ultrasound measurement of cervical length was completed, a region of interest of constant size was defined in the midsection of the posterior wall, and the tissue-specific gray scale was determined. Preterm delivery of <37 weeks of gestation was sought. RESULTS: Twenty-eight patients (41.2%) were delivered preterm. The risk for preterm delivery was increased significantly in patients with cervical length of ≤2.5cm (odds ratio, 7.67; 95% CI, 2.4-24.45), with Bishop score of ≥4 (odds ratio, 3.44; 95% CI, 1.21-9.75), and with decreased mean gray scale value (odds ratio, 12.13; 95% CI, 3.69-39.88). Parity and uterine contractions were not significant as predictors for preterm delivery, although the risk for preterm delivery increased with higher parity (odds ratio, 1.8; 95% CI, 0.68-4.79). The risk for preterm delivery remained nearly the same by uterine contractions (odds ratio, 0.92; 95% CI, 0.28-3.01). A mean scale value of ≤6.54 had the best cutoff value for the prediction of preterm delivery. For preterm delivery, a mean gray value ≤6.54 had a sensitivity of 82.1%, a specificity of 72.5%, a positive predictive value of 67.6%, and a negative predictive value 85.3%. Multiple logistic regression analysis indicated that, even when other variables are considered simultaneously, the mean gray scale value is the single best predictor of preterm delivery. CONCLUSION: Quantitative ultrasound tissue characterization of the uterine cervix predicts preterm delivery and provides additional information in the prediction of potential premature delivery.

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Dates
Created: 2006Issued: 2007-06-08Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2007.0335
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
GrauwertanalyseCervixinsuffizienzUterine cervixPremature birthUltrasound tissue characterisationBishop scoreBishop score
DFG-subjects
GebärmutterhalsVorzeitige WehenGynäkologieUltraschall / BilderzeugungDiagnostikFrühgeburt
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2007.0335
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Römer, Annette: Bewertung quantitativer sonografischer Gewebetypisierung und Längenbestimmung der Cervix uteri als neuer Prädiktor für Cervixinsuffizienz und Frühgeburtlichkeit. : Philipps-Universität Marburg 2007-06-08. DOI: https://doi.org/10.17192/z2007.0335.

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This item has been published with the following license: In Copyright