Revisionshäufigkeit und Revisionsgründe bei der Teleskopnagelung langer Röhrenknochen bei Patienten mit Osteogenesis imperfecta
Loading...
Files
Date
2025-10-21
Authors
Publisher
Philipps-Universität Marburg
item.page.supervisor-of-thesis
Abstract
Revision Rates and Causes in Telescopic Nailing of Long Bones in Patients with Osteogenesis Imperfecta
Osteogenesis Imperfecta (OI) is a rare genetic connective tissue disorder that leads to increased bone fragility and frequent fractures. Surgical treatment with intramedullary telescopic nailing is an established approach to stabilizing long bones in growing patients. The aim of this study was to analyze the revision rates and their causes following osteosynthetic treatment.
A retrospective analysis was conducted on 51 OI patients treated at Olgahospital Stuttgart between 2005 and 2024. Demographic data, OI classifications, surgical indications, and postoperative outcomes were recorded. A total of 208 primary surgeries were analyzed, focusing particularly on the necessity and frequency of revision surgeries.
The results indicate that, on average, 44.71% of initial implants required at least one revision surgery, with higher rates observed in patients with severe OI phenotypes. The main reasons for revisions included disease-related bone deformities, new trauma and surgery-related complications such as suboptimal fixation or inappropriate choice of osteosynthesis material. Fassier-Duval (FD) nails had significantly lower revision rates than Bailey-Dubow (BD) nails (p=0.002). Non-telescoping intramedullary nails, particularly trauma nails, showed a significantly lower revision rate compared to telescopic nails (p<0.001). Deformity correction in the presence of an acute fracture significantly reduced the number of required osteotomies (p=0.014).
This study highlights the importance of selecting appropriate implant materials and surgical techniques to reduce revision rates in OI patients. It recommends the preferential use of FD nails in growing patients and trauma nails in adults with completed bone growth. Further prospective studies are needed to refine surgical strategies and minimize complications.
Review
Metadata
Contributors
Supervisor:
Dates
Created: 2025Issued: 2025-10-21Updated: 2025-10-21
Faculty
Medizin
Language
ger
Data types
DoctoralThesis
DFG-subjects
Osteogenesis imperfectaRevisionFassier-Duval NagelChirurgische BehandlungOsteotomieBailey-Dubow NagelTeleskopnagelungOsteosynthese
DDC-Numbers
610
show more
Cansi, Safa: Revisionshäufigkeit und Revisionsgründe bei der Teleskopnagelung langer Röhrenknochen bei Patienten mit Osteogenesis imperfecta. : Philipps-Universität Marburg 2025-10-21. DOI: https://doi.org/10.17192/z2025.0457.