Item type:Thesis, Open Access

Hirnmorphometrische Auffälligkeiten bei Patienten mit Schizophrenie und ihre Assoziation mit kognitiven Defiziten

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Date

2007-04-12

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Philipps-Universität Marburg
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Abstract

We investigated morphometric changes in schizophrenic brains (total brain volume, cerebellum, hippocampus, SMA) with a ROI- analysis of structural MRI images. Also, we looked at cognitive deficits in the schizophrenic group (intelligence, memory, attention) and their correlation with structural abnormalities. We found a bilateral volume reduction of the hippocampus and memory deficits only in schizophrenic men. Impairments in the intelligence and attention domain were found for both male and female schizophrenic patients. Further, we found positive correlations of the volume of right hippocampus with visual memory and visual- constructive intelligence. Theories of a sexual dimorphism in schizophrenia are discussed in this study.

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Dates
Created: 2007Issued: 2007-04-12Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2007.0248
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
Supplemenär- motorisches KortexarealSMAMRISchizophreniaKognitive DefiziteSexual dimorphismHippocampusCognitive deficits
DFG-subjects
GeschlechtSchizophrenieKognitionHippocampus
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2007.0248
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Nehrkorn, Barbara (132897350): Hirnmorphometrische Auffälligkeiten bei Patienten mit Schizophrenie und ihre Assoziation mit kognitiven Defiziten. : Philipps-Universität Marburg 2007-04-12. DOI: https://doi.org/10.17192/z2007.0248.

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This item has been published with the following license: In Copyright