Einfluss der FFP-2-Maske auf die postoperative Wundinfektionsrate nach einer onkologischen kolorektalen Resektion während der COVID-19-Pandemie
Loading...
Files
Date
relationships.isAuthorOf
Publisher
Philipps-Universität Marburg
item.page.supervisor-of-thesis
Abstract
As of 2021, the COVID-19 pandemic led to raised hygiene standards both in everyday living
and in the health sector in order to prevent further spread of the virus. Among these is the
mandatory use of masks during patient care. In our institution, Johannes Wesling Klinikum
in Minden, Germany, a mandatory use of face masks was imposed as of the beginning of
2021 aiming to reduce the spread of airborne droplet infections.
The mainstay use of masks before the pandemic was during surgical procedures or
interventions to prevent wound contamination and thus postoperative surgical site
infections (SSI), although the evidence for this is inconclusive. Following this rationale, the
question now arises whether wearing FFP-2 masks intra- and perioperatively could have an
impact on the SSI rate compared to wearing standard surgical masks.
To clarify this question, we designed a study in which data of patients having undergone an
oncological operation in our institution between the beginning of 2016 and the end of 2021
was retrospectively gathered and evaluated. The primary endpoint was the development
of a SSI and the secondary endpoints were further complications as well as hospital and
intensive care unit length of stay. Two groups were formed: the first group consisting of
patients having undergone treatment before the mandatory use of FFP-2 masks and the
second consisting of patients treated during the mandatory use of FFP-2 masks.
A total of 458 patients were included, 366 were assigned to the standard surgical mask
group and 92 to the FFP-2 mask group. With overall good comparability of the groups, our
evaluation revealed no significant differences in the SSI rate or other recorded data
regarding the outcomes. Furthermore, a subgroup analysis in which patients with colon
and rectal cancer were individually evaluated and compared, revealed no significant
differences either. These groups were also comparable in terms of outcome.
To date, there has been no study known to us examining the influence of FFP-2 masks on
the SSI incidence specifically. However, studies examining the occurrence of SSI during the
COVID-19 pandemic regardless of type of mask used have been conducted. These studies
were able to demonstrate a significant decrease in the SSI rate since the outbreak of the
pandemic, which was mainly explained by stricter adherence to hand hygiene and a
reduction in hospital visits.
In a regression analysis we searched for possible predictors for SSI occurrence in our patient
collective, identifying the preoperative serum level of albumin as an independent
predictor. There is also some evidence in the literature that low preoperative serum
albumin is associated with significantly higher treatment costs.
In summary, this study showed no influence of FFP-2 masks on the SSI rate in oncological
resections of the colon or rectum. However, other studies indicate that the generally
stricter hygiene regulations during the pandemic can lead to a decrease in SSI rate.
In addition, this study was able to provide renewed evidence that the level of preoperative
albumin has an influence on the SSI rate. To further support these claims, a prospective,
randomized study would need to be conducted.
Review
Metadata
Contributors
Supervisor:
Dates
Created: 2022Issued: 2023-03-09Updated: 2023-03-09
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
OnkologieHygienepostoperative Komplikationen
DFG-subjects
ChirurgieWundinfektionenCovid-19FFPGesichtsmaskenkolorektal
DDC-Numbers
610
show more
Bohlmann, Laura: Einfluss der FFP-2-Maske auf die postoperative Wundinfektionsrate nach einer onkologischen kolorektalen Resektion während der COVID-19-Pandemie. : Philipps-Universität Marburg 2023-03-09. DOI: https://doi.org/10.17192/z2023.0151.