Item type:Thesis, Open Access

Genese und biologische Aktivität cerebraler Kavernome in adulten und pädiatrischen Patienten: eine immunhistochemische Studie von 87 Patienten

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Date

2006-11-15

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Publisher

Philipps-Universität Marburg
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Abstract

The thesis contributes to the illucidation of the genesis and the biological activity of cerebral cavernomas in adult and pediatric patients. The specimens of 87 patients suffering from cerebral cavernomas, who underwent surgery, were investigatet with immunohistochemical technique to give proof of the existance of relevant antigenes in the tissue. The cavernomas of patient groups with different clinical symptoms, as well as the cavernomas of adult patients compared to those of pediatric patients, had a different biological activity. Herewith the antigenes VEGF and Endoglin and the associated pathways play keyroles.

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Dates
Created: 2006Issued: 2006-11-15Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2006.0777
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
ImmunohistochemistryVEGFEndoglinCavernomasCerebral
DFG-subjects
Immunhistochemische StudieVEGFEndoglinAdulte vs. pädiatrische PatientenCerebrale KavernomeNeurochirurgie
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2006.0777
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Fremann, Sandra Maria (132258536): Genese und biologische Aktivität cerebraler Kavernome in adulten und pädiatrischen Patienten: eine immunhistochemische Studie von 87 Patienten. : Philipps-Universität Marburg 2006-11-15. DOI: https://doi.org/10.17192/z2006.0777.

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