Item type:Thesis, Open Access

Entwicklung der Hornhautendothelzelldichte (ECD)in der frühen postoperativen Phase nach Kataraktchirurgie in Abhängigkeit von der Verwendung einer hydroxypropylmethylcellulose-haltigen viskoelastischen Substanz versus Balanced Salt Solution während der Intraokularlinsen-Implantation

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Date

2015-02-02

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Philipps-Universität Marburg
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Abstract

In this prospective randomized study we compared the changes of endothelial cell density (ECD) in the early postoperative phase after cataract surgery depending on the use of HPMC containing viscoelastic or Balanced Salt Solution (BSS plus®) during the intraocular lens implantation. All participants had outpatient small incision phacoemulsification cataract surgery followed by implantation of a foldable acrylic one piece posterior chamber lens CT-Asphina® 409M (Carl Zeiss Meditec) or CT- Asphina® 409MV (Carl Zeiss Meditec). All surgeries were performed by a single experienced surgeon. In the BSS plus® sample the intraocular lens (IOL) implantation was carried out under continuous infusion and without any viscoelastic. 97 eyes of 69 participants underwent this procedure. The other sample comprising 87 eyes of 62 patients had IOL implantation under the viscoelastic Z- Celcoat®. The mean preoperative ECD was 2506 ± 310 cells/mm2 (BSS plus®) versus 2429 ± 262 cells/mm2 (Z-Celcoat®). After one week the cell count was 2348 ± 347 cells/mm2 (BSS plus®) versus 2297 ± 352 cells/mm2 (Z-Celcoat®). This corresponds to a decrease of 6.31 % in the BSS plus®-sample and 5.43% in the Z-Celcoat®-sample. Six weeks after surgery we measured a further decline of 1.49% and 1.09%, respectively. These changes were not significant. However, the surgical time in the BSS group with 7,2 ± 1,2 minutes was significantly shorter than 8,0 ± 1,4 minutes in the viscoelastic group. IOL-Implantation under BSS plus® infusion does not reduce ECD significantly, when compared to the implantation under viscoelastic. Moreover, it reduces surgical time by eliminating viscoelastic aspiration at the conclusion of the procedure.

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Dates
Created: 2014Issued: 2015-02-02
DOI
https://doi.org/10.17192/z2015.0053
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
BSS pluscorneal endothelial cell densityBSS plusIntraokularlinsenimplantationviscoelastic substancesviskoelastische SubstanzenHornhautendothelzelldichteintraocular lens implantation
DFG-subjects
KunststofflinseHornhautGrauer StarStaroperationHornhautendothel
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2015.0053
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Manojlovic, Irena: Entwicklung der Hornhautendothelzelldichte (ECD)in der frühen postoperativen Phase nach Kataraktchirurgie in Abhängigkeit von der Verwendung einer hydroxypropylmethylcellulose-haltigen viskoelastischen Substanz versus Balanced Salt Solution während der Intraokularlinsen-Implantation. : Philipps-Universität Marburg 2015-02-02. DOI: https://doi.org/10.17192/z2015.0053.

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