By means of immunhistochemical markers the expression of glial fibrillary acidic protein, vimentin and glykosphingolipid GD2 is investigated in 28 astrocytic tumors grading WHO II-IV. Statistically, there is found a high correlation in the cytoplasmatic expression of GFAP/GD2 as well as Vimentin/GD2 and GFAP/Vimentin.The semiquantitatively strongest expression was found in gemistocytic and protoplasmatic cells of the investigated glial tumors. As conclusion, astrocytic tumors express in a similar way intermediary filament GFAP and glykosphingolipid GD2. Whether or not a co-localisation of intermediary filaments and GD2 within the brain tumors takes place, remains open.
