Stellenwert der Punktscherwellen-Elastographie zur Dignitätseinschätzung mesenterialer Raumforderungen
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Philipps-Universität Marburg
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Abstract
7. Summary
Ultrasound elastography is a widely used diagnostic tool that provides reliable
information about the tissue stiffness of an organ. It is used in various organs such as
the liver, spleen, pancreas, kidney, prostate, breast and thyroid gland etc. At present,
there are no current recommendations/guidelines regarding its feasibility in the
mesentery.
In the present study, n= 69 patients with mesenteric masses were examined using ARFI
from September 2018 to November 2021. The aim was to differentiate the lesions based
on their tissue stiffness and the resulting mean ARFI velocity. The results showed that
the MAVs of the benign lesions were lower than the MAVs of the malignant lesions,
with an average value of 1.59 ± 0.93 m/s. The average value of the MAVs of the
malignant masses was 2.76 ± 1.01 m/s. The choice of the cut-off value of 2.05 m/s
resulted in a sensitivity of 75 % and a specificity of 70.3 % for the diagnosis of a
malignant mass (area under the curve = AUC = 0.802, 95% CI= 0.699-0.904). In the
subgroups of hematologic (n= 15) versus non-hematologic (n= 17) masses, both
subgroups showed a similarly high MAV of 2.73 ± 1.03 m/s and 2.79 ± 1.0 m/s,
respectively.
A comparison of the MAV values for mesenteritis (15/69; 21.7%) (1.53 ± 0.96 m/s)
revealed significantly lower values than those for malignant lesions overall (32/69;
46.6%) (2.76 ± 1.01 m/s; p= 0.001).
On B-scan ultrasound, no distinction could be made between benign and malignant
lesions with regard to the size of the mass. However, there was a significant difference
between the entities with regard to the echo behavior of the lesions, as low-echo masses
were significantly more frequently associated with malignancy (p= 0.001).
In view of the results presented, ARFI elastography is a non-invasive examination
method alongside B-scan US and CEUS for differentiating between benign and
malignant mesenteric masses. However, further prospective randomized studies are
required to validate the results of this study.
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Dates
Created: 2024Issued: 2024-10-30Updated: 2024-10-30
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
Punktscherwellen-ElastographieMesenteriale Raumforderungen
DDC-Numbers
610
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Kawohl, Svenja: Stellenwert der Punktscherwellen-Elastographie zur Dignitätseinschätzung mesenterialer Raumforderungen. : Philipps-Universität Marburg 2024-10-30. DOI: https://doi.org/10.17192/z2024.0335.
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This item has been published with the following license: In Copyright