Item type:Thesis, Open Access

Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II

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Date

2016-11-10

Authors

Publisher

Philipps-Universität Marburg
DOI

Supervisors

Abstract

Two pathological relevant proteins, human aldose reductase and human carbonic anhydrase, were used as model proteins to get insights into the process of molecular recognition. The thermodynamics and kinetics of the formation process of protein ligand complex formation were studied.

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Dates
Created: 2015Issued: 2016-11-10
DOI
https://doi.org/10.17192/z2015.0464
Faculty
Fachbereich Pharmazie
Publisher
Philipps-Universität Marburg
Language
eng
Data types
DoctoralThesis
Keywords
KineticProteinsDrug DesignLigandThermodynamic
DFG-subjects
LigandKinetikThermodynamikArzneimitteldesignProteine
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2015.0464
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Rechlin, Chris: Insights into Protein-Ligand Molecular Recognition: Thermodynamic, Kinetic and Structural Characterization of Inhibitor Binding to Aldose Reductase and Carbonic Anhydrase II. : Philipps-Universität Marburg 2016-11-10. DOI: https://doi.org/10.17192/z2015.0464.

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This item has been published with the following license: In Copyright