In this thesis the selforganisation of molecular
capsules in polar solvents from calix[4]arene building blocks
with four ionic gruops was studied with Job plots, NMR
titrations, NOESY experiments as well as ESI-MS measurements.
ESI-MS(/MS) has been used as a method which allows the fast,
specific and sensitive simultaneous detection and relative
stability approximation of supramolecular assemblies in
mixtures. MS/MS experiments reveal the same relative order of
gas phase stabilities as previously found in solution.
Furthermore, the amphiphilic Calix[4]arenetetraphosphonate
receptors were embedded in lipid monolayers at the air/water
interface. This system is able to distinguish between proteins
of varying pI at nanomolar concentrations.
