Item type:Thesis, Open Access

Die Bedeutung der Surfactantproteine SP-A und SP-D bei der Modulation des Entzündungsprozesses im Rahmen des chronischen Asthma bronchiale

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Date

2011-05-12

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Philipps-Universität Marburg
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Abstract

The function of the surfactant proteins SP-A ans SP-D in modulation of chronic asthma are not completly examined. The aims of this study were to investigate further the interactions between SP-A and SP-D and type II pneumocytes using a murine model of chronic asthma. After challenging the animals different cytokine receptors - inflammatory and antiinflammatory ones - were detected by PCR and immunohistology. We found an upregulation of proinflammatory cytokine receptors in abscence of SP-D while these receptors were reduced in absence of SP-A.

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Dates
Created: 2011Issued: 2011-05-12Updated: 2011-08-08
DOI
https://doi.org/10.17192/z2011.0353
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
SP-DAsthma, SP-ASP-DAsthmaSP-AInterleukine
DFG-subjects
SP-ASP-DAsthmaInterleukineInterleukinrezeptoren
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2011.0353
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Diogo, Isabell (1011457008): Die Bedeutung der Surfactantproteine SP-A und SP-D bei der Modulation des Entzündungsprozesses im Rahmen des chronischen Asthma bronchiale. : Philipps-Universität Marburg 2011-05-12. DOI: https://doi.org/10.17192/z2011.0353.

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This item has been published with the following license: In Copyright