Item type:Thesis, Open Access

Die prognostische Signifikanz eines perinodalen Wachstums bei Patienten mit Plattenepithelkarzinom im Kopf- Hals- Bereich - Eine Metaanalyse-

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Date

2006-10-05

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Philipps-Universität Marburg
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Abstract

To assess the risk factor of capsular rupture for individual prognosis and potential therapeutic decision making, the present meta- analsis elaborated the prognostic significance of perinodal spread in a large group of patients suffering from HNSCC. A review of the published literature was conducted, and fixed and random effects models were applied for estimation of the summarized odds ratio and 95% confidence intervals, including a test for homogeneity of the odds ratios. Study methology allowed the enrollment of only 9 studies of 115 published papers. Excluded studies lacked regarding primary tumour location, number and location of lymph node metastases, values on five- year survival, or adequate follow- up data. A summarized odds ratio of 2.7 leads to the conclusion that perinodal spread negatively impacts the five year survival.

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Dates
Created: 2006Issued: 2006-10-05Updated: 2011-08-10
DOI
https://doi.org/10.17192/z2006.0640
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
Prognostic significanceHNSCCCancerKapselruptur5- Jahres- ÜberlebenPerinodal spreadExtracapsular spread
DFG-subjects
Prognostische SignifikanzPerinodales WachstumPlattenepithelkarzinom
DDC-Numbers
610
License
https://rightsstatements.org/vocab/InC-NC/1.0/
URI
https://open.uni-marburg.de/handle/10.17192/z2006.0640
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Kessel, Kristina (132142783): Die prognostische Signifikanz eines perinodalen Wachstums bei Patienten mit Plattenepithelkarzinom im Kopf- Hals- Bereich - Eine Metaanalyse-. : Philipps-Universität Marburg 2006-10-05. DOI: https://doi.org/10.17192/z2006.0640.

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