Hooked on a feeling - Eine Pilotstudie zur Untersuchung neuronaler Korrelate des Einflusses von Musikhören auf Stresserleben und -reduktion: Eine detaillierte Betrachtung von biochemischen, physiologischen, verhaltenstypischen und neuronalen Korrelaten einer akustischen Intervention bei Stress.
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Philipps-Universität Marburg
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Abstract
This study „Hooked on a feeling – Eine Pilotstudie zur Untersuchung neuronaler Korrelate des Einflusses von Musikhören auf Stresserleben und -reduktion: Eine detaillierte Betrachtung von biochemischen, physiologischen, verhaltenstypischen und neuronalen Korrelaten einer akustischen Intervention bei Stress“ researches the influence of acoustic interventions on stress. It focuses on neural interactions as well as biochemical, physiological and behavioural responses to stress.
The experiment’s section on acoustic intervention is the main subject of this thesis.
This work not only aims to reproduce the biophysiological human reactions to stress and stress-reduction after acoustic intervention already shown in other studies, but to additionally use magnetic resonance imaging to show neural correlates of the influence of acoustic interventions on stress.
Especially the feasibility of such an experiment in the environment of magnetic resonance imaging is the main subject of research of this study. It aims to differentiate between two different acoustic interventions and their influence on stress on a neural level.
Building on the most recent works in this field, we developed the hypothesis that music as an acoustic intervention could cause a much deeper stress-reduction or prevent the possibility of the induction of stress much more than natural sounds would be able to.
Especially the Amygdala, Hypothalamus, Hippocampus and prefrontal cortex are the neural correlates on which this study expects to see some change of the neural interaction’s intensity while listening to music. These important areas of emotion- regulation should be contacted more intensely by neurons from the auditory cortical area during music listening than during natural sound interplay. This interaction should cause a stress reducing effect.
This study seeks to evaluate music as a therapeutic instrument for stress reducing interventions for daily life as well as to prevent chronic diseases caused by stress. It could also serve as a supplement to already existing stress coping mechanisms and therapies.
The results of this experiment show a particularly good feasibility of the stresstest which is conducted during magnet resonance imaging. The provocation of stress and its reduction under an acoustic intervention works excellently.
Nevertheless, significant difference between the two acoustic stimuli, music and natural sounds were not observed. These findings were constant in all the experiment’s varied measurements. The analysis included biochemical analysis of cortisol and alpha amylase of saliva samples, physiological parameters such as heartrate and electrodermal response as well as psychometric evaluations of the subjective conception of stress.
Comparing the two acoustic conditions, the neuronal analysis of connectivity during stress-reduction showed no significant difference in the strength of neural connectivity, possibly explaining the occurrence of stress-reduction.
A significant difference can be found comparing the part of the experiment where stress-induction and stress-reduction takes place.
These results may allow to conclude that the feasibility of the setting of the described study of stress and stressreducing mechanisms in the environment of magnet resonance imaging is possible only with limitations. We discuss the possibility to transfer the setting into other environments that are more compatible to the design and technical requirements. Alternatively the usage of electroencephalography supplemented by near infrared spectography. The stresstest used in this study can be re-evaluated and confirmed with the results mentioned. This innovation opens new possibilities for studies to examine stress and neuronal correlates during magnet resonance imaging. It remains to critically scrutinize other methods used in this study and their feasibility and practicability. The procedure of taking saliva samples and therefore disrupting the ongoing experiment could have caused major outliers and the additional technical advice inhibited an examination of neuronal correlates with no acoustic intervention.
Thus, there can be no exact conclusion as to the role music plays for a therapeutic stress-reduction.
Regarding the results and discussion, we can conclude that this study shows a very good practicability of the used stresstest. Comparing stress-reduction effects of music and natural sounds, no significant differences were found. On that basis, the hypothesis that music would cause more stress-reduction than natural sounds has to be rejected.
When looking at previously described technical limitations of magnetic resonance imaging, we can state that the setting of this examination has extensive influence on the results. A reproduction of this study on a large scale and with complementary material and methods should be conducted to re-approve the hypothesis and to evaluate music as therapeutic instrument further.
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Dates
Created: 2021Issued: 2021-11-02Updated: 2021-11-02
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
measurements of physiological and behavioral dataMessung physiologischer und behavioraler Daten im MRTStressreduction via music and natural soundsneuronal correlates of stressStressreduktion durch Musik und NaturgeräuscheMRIneuronale Bildgebung von Stress
DFG-subjects
Alpha AmylaseMusikStressneuronale Korrelate,CortisolStressreduktionMRTTSST
DDC-Numbers
610
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Terhorst, Rebekka: Hooked on a feeling - Eine Pilotstudie zur Untersuchung neuronaler Korrelate des Einflusses von Musikhören auf Stresserleben und -reduktion: Eine detaillierte Betrachtung von biochemischen, physiologischen, verhaltenstypischen und neuronalen Korrelaten einer akustischen Intervention bei Stress.. : Philipps-Universität Marburg 2021-11-02. DOI: https://doi.org/10.17192/z2021.0362.