Vergleich zwischen DXA und sechs verschiedenen quantitativen Ultraschallgeräten (QUS) bei Frauen mit Hüftfraktur
Loading...
Files
Date
Authors
Publisher
Philipps-Universität Marburg
Supervisors
Abstract
OBJECTIVES:
Dual-energy X-ray absorptiometry (DXA) is the gold standard for assessment of bone mineral density, an important risk factor for osteoporotic fractures. Recent reports suggest that quantitative ultrasonometry (QUS) is able to predict fractures; however, only limited data in women with hip fractures are available.
METHODS:
We examined 91 postmenopausal women who had sustained an osteoporosis-related hip fracture within the past 7 days using DXA and six different QUS devices and compared them with 91 healthy age-matched controls.
RESULTS:
Femoral neck (FN), total hip (TH) and lumbar spine (LS) T-scores were lower in women with hip fractures compared to matched controls: - 2.38 vs. - 1.64 (p < 0.001), - 2.36 vs. - 1.44 (p < 0.001) and - 2.05 vs. - 1.50 (p = 0.41), respectively. The T-scores of the Achilles, Sahara, InSight and Omnisence QUS devices were also lower in patients with hip fractures compared to matched controls: - 3.20 vs. - 2.36 (p < 0.001), - 2.196 vs. - 1.761 (p = 0.005), - 2.631 vs. - 1.849 (p < 0.001), - 3.707 vs. - 3.030 (p = 0.032), respectively. However, the T-scores of the DBM and QUS-2 did not differ between the two groups: - 4.543 vs. - 4.324 (p = 0.352) and - 1.7 vs. - 2.0 (p = 0.465), respectively. Compared to DXA (hip), the odds ratios of the Achilles, InSight and Sahara were comparable, while the odds ratios of the DBM, Omnisence and QUS-2 were significantly lower (p ≤ 0.05).
CONCLUSIONS:
Compared to DXA, the Achilles, Sahara and InSight QUS devices showed similar hip fracture discrimination while the DBM, Omnisence and QUS-2 did not. Therefore, some QUS devices are able to identify a clinically meaningful risk factor in women at high risk of hip fracture.
Review
Metadata
Contributors
Supervisor:
Dates
Created: 2018Issued: 2019-04-24Updated: 2019-04-24
Faculty
Medizin
Publisher
Philipps-Universität Marburg
Language
ger
Data types
DoctoralThesis
Keywords
osteoporosisorthopedicsOsteoporoseQUSquantitative ultrasoundpostmenopausal womengynecologyQUShip fractureDXAGynäkologiePostmenopausale FrauenOrthopädieDXAKnochendichtemessungbone densitySchenkelhalsfraktur
DFG-subjects
FrauenDXAQuantitativer UltraschallSchenkelhalsfrakturOsteoporoseQUSKnochendichtemessung
DDC-Numbers
610
show more
Imani-Mollaiyan, Padideh: Vergleich zwischen DXA und sechs verschiedenen quantitativen Ultraschallgeräten (QUS) bei Frauen mit Hüftfraktur. : Philipps-Universität Marburg 2019-04-24. DOI: https://doi.org/10.17192/z2018.0423.