Diagnostic Accuracy of Sonoelastography for Breast Lesions: A Meta-Analysis Comparing Strain and Shear Wave Elastography
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MDPI
Abstract
This meta-analysis evaluated the diagnostic accuracy of sonoelastography for distinguishing
benign and malignant breast lesions, comparing strain elastography and shear wave
elastography (SWE). We systematically reviewed 825 publications, selecting 30 studies
(6200 lesions: 45% benign, 55% malignant). The pooled sensitivity and specificity for overall
sonoelastography were 88% (95% CI: 85–91%) and 84% (95% CI: 81–87%), respectively.
Strain elastography showed sensitivity and specificity of 85% and 80%, respectively, while
SWE demonstrated superior performance with 90% sensitivity, 86% specificity, and an
AUC of 0.92. Moderate heterogeneity (I2 = 55%) was attributed to study variation. SWE
showed the potential to reduce unnecessary biopsies by 30–40% by increasing specificity.
AI-assisted image analysis and standardized protocols may enhance accuracy and reduce
variability. These findings support the integration of SWE into breast imaging protocols.
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Except where otherwised noted, this item's license is described as Attribution 4.0 International